European Surveillance of
infections and their risk factors in trauma patients (ESIT)
A Project of the European Society of
Biomodulation and Chemotherapy
Trauma infection network
The primary objectives are:
- To establish an interdisciplinary study group "Infections in Traumatology"
- To implement a surveillance system for trauma patients with a standardized documentation
programme (data set) in at least 10 centers of traumatic and orthopedic surgery in order
to generate representative data of good quality on
- Incidence and types of infectious complications in trauma patients, especially bone and
- Microbiology and resistance patterns of causative microorgansims,
- Prophylaxis and treatment of infections with antibiotics and other antiinfective agents.
- Conduct of multicenter clinical studies in order to optimize therapy of acute and
chronic osteomyelitis as well as prostetic device infections.
- Prepare and publish guidelines for prevention and treatment of infections in trauma
- To assess the incidence of infections depending on trauma topography, severity of trauma
(e.g. fractures and soft tissue) as well as on the type of prosthetic device.
- Identification of factors in trauma management which possibly influence the development
of infection (e.g. time period of primary diagnostics and primary care, points of time of
emergency and delayed elective surgery).
- Analysis of treatment policies and efficacy of antibiotics in perioperative prophylaxis
and treatment of infections.
- To prepare resistance profiles of causative pathogens being the basis for specific
- Conduct of clinical studies based on qualitiative representative data from large
homogeneous patient groups mit identical trauma type and topography.
ã ESBiC Datacenter Munich, 1999